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BACKTRACKING: UNVEILING AN ADDITIONAL LAYER OF GENE REGULATION

2/9/2024

A recent pioneering technique, Long Range Cleavage sequencing (LORAX-seq), has been developed by researchers at NYU Langone Health to detect 'backtracking' events in the genetic material (genome) of various species. Backtracking, where RNA polymerase slips backward along the DNA chain during transcription, is a commonly occurring form of gene regulation. It happens frequently, persists longer than previously thought, and serves functions beyond DNA repair, potentially influencing gene expression and development. This research underscores its relevance in understanding diseases like cancer and aging, offering insights for potential therapeutic interventions.

More reading
Persistence of backtracking by human RNA polymerase II
Kevin B. Yang, Aviram Rasouly, Vitaly Epshtein, Thao Nguyen, Ilya Shamovsky, Evgeny Nudler, etc
DOI:https://doi.org/10.1016/j.molcel.2024.01.019

hERE we cOME!

2/9/2024

Established in December 2018, Minnebio has evolved into a sustainable supplier within the biotechnology sector. Our specialization encompasses enzymes such as Ultra-Active Nuclease (also known as Benzonase) and Proteinase K, along with cytokines including human interleukins-2, 6, 10, 12, 15, and cell culture media. These offerings cater to both academic research and pharmaceutical development needs.

At Minnebio, we are committed to delivering top-tier products that are both high quality and cost-effective, while prioritizing customer satisfaction through tailored solutions.

As we swiftly progress into a rapid development phase, we remain dedicated to advancing science and staying forefront of biotechnological advancements. Through our blog, we aim to disseminate the latest innovations and discoveries to individuals interested in the field of biotechnology. By leveraging our expertise, we assist customers in finding optimal solutions for their research and development ventures.

At Minnebio, we embrace collaborative efforts to achieve our shared goals in scientific advancement.